Quick Answer: What Type Of Drug Is Spinraza?

How much does Spinraza cost?

The catch is that Spinraza costs hundreds of thousands of dollars a year.

The first year of Spinraza treament, which is administered through a spinal tap, costs more than $700,000, with the cost of treatment in the following years hovering around $300,000..

Is SMA painful?

Overall, pain in this population of SMA patients appears to be comparable to that of people with osteoarthritis or chronic low back pain. Despite SMA patients being generally protected from severe pain, younger SMA patients do experience pain at heightened rates.

What is Spinraza used for?

The U.S. Food and Drug Administration today approved Spinraza (nusinersen), the first drug approved to treat children and adults with spinal muscular atrophy (SMA), a rare and often fatal genetic disease affecting muscle strength and movement.

Who makes Spinraza?

After the pre-clinical work and early clinical testing was complete, Ionis Pharmaceuticals partnered with Biogen to launch a number of clinical trials testing Spinraza.

What kind of drug is Spinraza?

Nusinersen, marketed as Spinraza, is a medication used in treating spinal muscular atrophy (SMA), a rare neuromuscular disorder. In December 2016, it became the first approved drug used in treating this disorder. Nusinersen has orphan drug designation in the United States and the European Union.

Why is Spinraza so expensive?

by Drugs.com The reason Zolgensma is so expensive is because that is the price Novartis has decided it is worth because it “dramatically transforms the lives of families affected by this devastating disease” and the claimed cost of bringing new drugs to market.

What is the life expectancy of spinal muscular atrophy?

Symptoms usually appear around 18 months of age or in early childhood. Children with this type of SMA generally have an almost normal life expectancy. Type 4 is very rare. It usually starts in young adulthood, and causes mild motor impairment.

How effective is Spinraza?

Another study assessed Spinraza’s effectiveness in children whose SMA was less severe and diagnosed at a later stage (average age of 3 years). After 15 months of treatment, 57% of children receiving Spinraza showed improvement in movement compared with 26% of children on placebo.

Is Spinraza covered by insurance?

The medical policy for SPINRAZA can vary from plan to plan. For instance, the FDA has approved SPINRAZA for use in both children and adults. However, some health plans may not cover patients of all ages.

When was Spinraza approved?

On December 23, 2016, the US Food & Drug Administration (FDA) approved SPINRAZA (nusinersen), the first drug approved for the treatment of spinal muscular atrophy (SMA) in pediatric and adult patients.

Does Spinraza Cure SMA?

Multiple research studies, called clinical trials, have demonstrated that the drug significantly slows the disease’s progression and, in many cases, improves the strength of individuals with SMA. The drug is beneficial in approximately 40 percent of patients who receive it.

Is Spinraza covered by Medicare?

Medicare does cover it, I was told they cover anything approved by the FDA. But if all you have is Medicare, be aware they only cover 80% of the cost (it’s covered under part B, not D) and you’re supposed to be responsible for the remainder.

What is Spinraza made of?

Spinraza contains an antisense oligonucleotide that allows the body to produce more of a protein called survival motor neuron (SMN). SMN is essential for the health of motor neurons, nerve cells that control the movement of muscles.

Is there a cure for SMA?

It’s not currently possible to cure spinal muscular atrophy (SMA), but research is ongoing to find new treatments. Treatment and support is available to manage the symptoms and help people with the condition have the best possible quality of life.

Is Spinraza a gene therapy?

While Zolgensma is a gene therapy that aims to correct the genetic defect that causes the disease, Spinraza works by increasing the amount of full-length SMS protein that is critical to maintaining motor neurons.